dariaartamonova

Daria Artamonova

Research Scientist
Center of Life Sciences

Experimental validation of predicted CRISPR effectors for creation of improved genome editing tools

  1. You L, Ma J, Wang J, Artamonova D, Wang M, Liu L, Severinov K, Zhang X, and Wang Y. (2018) Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference. Cell, in press 
  2. Semenova E, Savitskaya E, Musharova O, Strotskaya A, Vorontsova* D, Datsenko KA, Logacheva MD, Severinov K. (2016) Highly efficient primed spacer acquisition from targets destroyed by the Escherichia coli type I-E CRISPR-Cas interfering complex. Proc Natl Acad Sci U S A, 113(27): 7626-31. doi: 10.1073/pnas.1602639113
  3. Vorontsova D, Datsenko KA, Medvedeva S, Bondy-Denomy J, Savitskaya EE, Pougach K, Logacheva M, Wiedenheft B, Davidson AR, Severinov K, Semenova E. (2015) Foreign DNA acquisition by the I-F CRISPR-Cas system requires all components of the interference machinery. Nucleic Acids Res., 43(22): 10848-60. doi: 10.1093/nar/gkv1261.
  4. Yakunina MV, Vorontsova DN, Minakhin LS. (2013) Non-canonical RNA-polymerases of jKZ-like phages. Petersburg State Polytechnical University Journal, 1(165): 120-127. (in Russian)
  5. Kasumu AW, Hougaard C, Rode F, Jacobsen TA, Sabatier JM, Eriksen BL, Strøbæk D, Liang X, Egorova P,Vorontsova D, Christophersen P, Rønn LC, Bezprozvanny I. (2012) Selective positive modulator of calcium-activated potassium channels exerts beneficial effects in a mouse model of spinocerebellar ataxia type 2. Chemistry and Biology, 19 (10): 1340-1353. doi: 10.1016/j.chembiol.2012.07.013.
  6. Kasumu AW, Liang X, Egorova P,Vorontsova D, Bezprozvanny I. (2012) Chronic suppression of inositol 1,4,5-triphosphate receptor-mediated calcium signaling in cerebellar purkinje cells alleviates pathological phenotype in spinocerebellar ataxia 2 mice. J Neuroscience, 32 (37): 1643-12. doi: 10.1523/JNEUROSCI.1643-12.2012.
  7. Livinskaya VA, Ivanov VA, Fedorova OA, Vorontsova DN, Barlev NA, Nikiforov AA. (2012) Polyclonal antibodies against human proteasome subunits PSMA3, PSMA5, and PSMB5. Hybridoma (Larchmt), 31(4): 272-278. doi: 10.1089/hyb.2012.0004.

2017 – PhD in Life Science, Skolkovo Institute of Science and Technology, Center for Life Science

2013 – Master in Physics, Saint Petersburg State Polytechnical University, Department of Biophysics

Gene Engineering, CRISPR-Cas systems

2015 – grant UMNIK “Development of antibiotic-independent screening gene deletions method using the inactivation of genes in thermophilic bacteria Thermus thermophilus