Tatiana Abakumova

• Development of the hepatocellular carcinoma fast model in mice
• Magnetic nanoparticles and carbon nanotubes as enhancers for targeted RNA delivery in vivo

1. Abakumov M.A., Grinenko N.F., Baklaushev V.P., Sandalova T.O., Nukolova N.V., Semenova A.V., Sokolsky-Papkov M, Vishvasrao H, Kabanov A.V., Chekhonin V.P. Tumor-specific contrast agent based on ferric oxide superparamagnetic nanoparticles for visualization of gliomas by magnetic resonance tomography Bull Exp Biol Med. 2012; 153(1) :89-93. IF= 0,456
2. Abakumov M.A., Shein S.A., Vishvasrao H., Nukolova N.V., Sokol’ski-Papkov M., Sandalova T.O., Gubskii I.L., Grinenko N.F., Kabanov A.V., Chekhonin V.P. Visualization of experimental glioma C6 by MRI with magnetic nanoparticles conjugated with monoclonal antibodies to vascular endothelial growth factor. Bull Exp Biol Med. 2012; 154(2): 274-7. IF= 0,456
3. Nukolova N.V., Baklaushev V.P., Abakumova T.O., Melnikov P.A., Abakumov M.A., Yusubalieva G.M., Bychkov D.A., Kabanov A.V., Chekhonin V.P.Targeted delivery of cisplatin by сonnexin 43 vector nanogels to the focus of experimental glioma C6. Bull Exp Biol Med. 2014; 157(4): 524-9. IF= 0,456
4. Shein S.A., Nukolova N.V., Korchagina A.A., Abakumova T.O., Kiuznetsov I.I., Abakumov M.A., Baklaushev V.P., Gurina O.I., Chekhonin V.P. Site-directed delivery of VEGF-targeted liposomes into intracranial C6 glioma. Bull Exp Biol Med. 2015; 158(3): 371-6. IF= 0,456
5. Abakumova T.O., Nukolova N.V., Gusev E.I., Chekhonin V.P. MRI contrast agents in diagnostics of multiple sclerosis. Zh Nevrol Psikhiatr Im S S Korsakova. 2015, 115(1):58-65.
6. Abakumova T.O., Kuzkina A.A., Zharova M.V., Pozdeeva D.A., Gubskii I.L., Shepeleva I.I., Antonova O.M., Nukolova N.V., Kekelidze Z.I., Chekhonin V.P.Cuprizone Model as a Tool for Preclinical Studies of the Efficacy of Multiple Sclerosis Diagnosis and Therapy. Bull Exp Biol Med. 2015 Jun 2; 159(1):111-5 IF= 0,456
7. Abakumov M.A., Nukolova N.V., Sokolsky-Papkov M., Shein S.A., Sandalova T.O., Vishwasrao H., Grinenko N.F., Gubsky I.L., Abakumov A.M., Kabanov A.V., Chekhonin V.P. VEGF-targeted magnetic nanoparticles for MRI visualization of brain tumor. Nanomedicine. 2015 May;11(4):825-33
8. Abakumova T.O., Abakumov M.A., Shein S.A., Chelushkin P.S., Bychkov D.A., Mukhin V.Y., Yusubalieva G.M., Grinenko N.F., Kabanov A.V., Nukolova N.V., Chekhonin V.P. Connexin 43-targeted T1-contrast agent for MRI diagnostics of glioma. Contrast media and molecular imaging, 2016, 11(1):15-23 Impact factor = 3.307
9. Shein S.A, Kuznetsov I.I., Abakumova T.O., Chelushkin P.S., Korchagina A.A., Bychkov A., Seregina I.F., Bolshov M.A., Kabanov A.V., Chekhonin V.P., Nukolova N.V. VEGF and VEGFR2-targeted Liposomes for Cisplatin Delivery to Glioma Cells Molecular Pharmoceutics, 2016, 13(11):3712-3723 IF = 4,44
10. Voeikov R.V., Abakumova Т.О., Grinenko N.Ph., Melnikov P.A., Bespalov V.A., Stukov S., Chekhonin V.P., Klyachko N.L. and Nukolova N.V. Dioxadet–loaded nanogels as a potential formulation for glioblastoma treatment. Journal of Pharmaceutical Investigation,  47(1), pp 75–83
11. Baklaushev VP, Kilpeläinen A, Petkov S, Abakumov MA, Grinenko NF, Yusubalieva GM, Latanova A A, Gubskiy IL, Zabozlaev FG, Starodubova E, Abakumova TO, Isaguliants MG, Chekhonin V.P. Luciferase expression allowa bioluminescence imaging but imposes limitations on the orthotopic mouse (4T1) model of breast cancer. Scientific Reports 7, Article number: 7715 (2017); IF  = 4,259
12. V. Nukolova, A.D. Aleksashkin, T.O. Abakumova, A.Y. Morozova, I.L. Gubskiy, Е.А. Kirzhanova, M.A. Abakumov, V.P. Chekhonin, c, N.L. Klyachko, A.V. Kabanov Multilayer polyion complex nanoformulations of superoxide dismutase 1 for acute spinal cord injury Journal of Controlled Release, volume 270, 28 January 2018, Pages 226-236 IF = 7,56
13. Semkina A.S.; Abakumov M.A., Skorikov A.S.; Abakumova T.O., Melnikov P.A., Grinenko N.F.; Cherepanov S.A., Vishnevskiy D.A.; Naumenko V.A.; Ionova K.P., Majouga, A.G., Chekhonin V.P. Multimodal doxorubicin loaded magnetic nanoparticles for VEGF targeted theranostics of breast cancer. Nanomedicine: Nanotechnology, Biology, and Medicine, 2018 IF = 5.7 (accepted)

2006-2012                  M.Sc., Pirogov Russian National Research Medical University, Department of Medical Biology, Department of Medical Nanobiotechnology

2012-2015                  Ph.D. in Biology “Gd-based contrast agent for MRI diagnosis of glioma and demyelination” (Scientific advisor Prof. Vladimir P. Chekhonin)

2016                            Сertified advanced training program  «Modern animal facility and experimental work with SPF animals»

targeted delivery of nanoparticles, blood-brain barrier permeability, MRI contrast agents, gadolinium, iron oxide nanoparticles, monoclonal antibodies, animal models, glioma c6, multiple sclerosis

2011 Second Award at the 6th International Pirogov Scientific Conference of Students and Young Scientists in Moscow

2012 First Award at 7th International Pirogov Scientific Conference of Students and Young Scientists; Third Award, International conference «Biotechnology Biotechnology: State of the Art and Prospects of Development” in Moscow; Second Award, 19th International Scientific Conference of Students and Young Scientists «Lomonosov»; Award, 3rd International Congress on “Biomaterials and Nanobiomaterials: Recent Advances Safety – Toxicology and Ecology Issues” in Heraclion, Greece; Scholarship of the “Green Light” fund; Scholarship of the government of the Russian Federation

2013 Award of «Invitro» company

2014 Fellowship of the 10th International Symposium of Polymer Therapeutics in Valencia, Spain, Winner of Young Scientist Award, 12th International Conference on Nanostructured Materials (NANO), July 13-18, 2014

2015 First Place Award for poster presentation, conference “Magnetic nanoparticles in biology and medicine”, Zvenigorod