“Dynamic nanophotonic sensing systems development for the
real-time concentration measurement of cortisol for the in vitro and in vivo studies”
Based on our group project – Surface-specific Metal-enhanced Fluoroimmunoassay development for time-resolved monitoring of Cortisol concentration, performing in vitro, currently we are working together with Professor V.Drachev and Y.Kotelevtsev to optimize biochemical components of the assay and to apply the system to polymer optical fiber probe surface to achieve in vivo sensing.
1. Surface-specific washing-free immunosensor for time-resolved cortisol monitoring. Sofia M. Safarian, Pavel A. Kusov, Sergey S. Kosolobov, Oksana V. Borzenkova, Artem V. Khakimov, Yuri V. Kotelevtsev, Vladimir P. Drachev. Talanta Volume 225, 122070 Available online 29 December 2020.
2. Development of a multiplex PCR test system for the determination of a transgene based on the pBC1 plasmid and its derivatives for the expression of recombinant proteins in Mus musculus milk V. A. Kalmykov, P. A. Kusov, A. V. Deykin Doklady Biochemistry and Biophysics,Volume 485, Issue 1, pp 153–156 Mar 2019
3. New personalized genetic mouse model of Lesch-Nyhan syndrome for pharmacology and gene therapy V. A. Kalmykov, P. A. Kusov, M. I. Yablonskaia, E. N. Korshunov, D. S. Korshunova, M. V. Kubekina, Y. Y. Silaeva, A. V. Deykin, N. E. Lukyanov Research Results in Pharmacology 4(4): 115–122 2018 Dec
2016 – M.Sc. with excellence;
2017 – NCBMB Russian Academy of Sciences Biochemical Society membership 1203/003/2018/RBSMEM
2021 – Foundation for assistance to small innovative enterprises (FASIE) – Umnik Grant, project for the development of implantable cortisol monitoring device based on plasmonic-active fluoroassay on optical fiber.