Natalia Morozova

Research Intern
Center of Life Sciences

Using live microscopy to understand the effects of CRISPR defense on phage infection at single-cell level.

1.Morozova N.E., Vedyaykin A.D., Sabantsev A.V., Pobegalov G.E., Murashov S.V., Khodorkovskii M.A. Formation of membrane tubular structures from human hepatocytes. Scientific and technical journal of SPbSTU. Physical and mathematical sciences. 2013;3(177):167-76.

2. Vedyaykin AD, Morozova NE, Pobegalov GE, Arseniev AN, Khodorkoskii MA, Sabantsev AV. Study of hepatocyte plasma membrane mechanical properties using optical trapping. J Phys Conf Ser. 2014;572. doi: Artn 012016. doi:10.1088/1742-6596/572/1/012016. PubMed PMID: WOS:000347871000016.

3. Pobegalov G, Cherevatenko G, Alekseev A, Sabantsev A, Kovaleva O, Vedyaykin A, Morozova N, Baitin D, Khodorkovskii M. Deinococcus radiodurans RecA nucleoprotein filaments characterized at the single-molecule level with optical tweezers. Biochemical and biophysical research communications. 2015; 466(3):426-30. doi: 10.1016/j.bbrc.2015.09.042 (

4. Morozova N, Sabantsev A, Bogdanova E, Fedorova Y, Maikova A, Vedyaykin A, et al. Temporal dynamics of methyltransferase and restriction endonuclease accumulation in individual cells after introducing a restriction-modification system. Nucleic Acids Res. 2016;44(2):790-800. doi: 10.1093/nar/gkv1490. PubMed PMID: 26687717; PubMed Central PMCID: PMC4737168.

5. AD Vedyaykin, AV Sabantsev, IE Vishnyakov, NE Morozova, VS Polinovskaya, Khodorkovskii M. 3D super-resolution microscopy of bacterial division machinery. Journal of Physics: Conference Series. 2016;741(1). doi: 10.1088/1742-6596/741/1/012066.

6. Alexandra Strotskaya, Ekaterina Savitskaya, Anastasia Metlitskaya, Natalia Morozova, Kirill A. Datsenko, Ekaterina Semenova, Konstantin Severinov. The action of Escherichia coli CRISPR–Cas system on lytic bacteriophages with different lifestyles and development strategies. Nucleic Acids Res. 2017; 45 (4): 1946-1957. doi:10.1093/nar/gkx042

7.Vedyaykin A.D., Sabantsev A.V., Vishnyakov I.E., Vishnyakov I.E., Morozova N.E., Khodorkovskii M.A. Recovery of division process in bacterial cells after induction of SulA protein which is responsible for cytokinesis arrest during SOS – response. Cell and Tissue Biology. 2017; 11(2): 89-94. doi: 10.1134/S1990519X17020080 (

8. B. Wilcox, I. Osterman, M. Serebryakova, D. Lukyanov, E. Komarova, B. Gollan, N. Morozova, Y.I. Wolf, K.S. Makarova, S. Helaine, P. Sergiev, S. Dubiley, S. Borukhov, K. Severinov. Escherichia coli ItaT is a type II toxin that inhibits translation by acetylating isoleucyl-tRNAIle. // Nucleic Acids Res, 2018. doi: 10.1093/nar/gky560, PMID: 29931259, (

9. Gordeeva J, Morozova N, Sierro N, Isaev A, Sinkunas T, Tsvetkova K, Matlashov M, Truncaite L, Morgan RD, Ivanov NV, Siksnys V, Zeng L, Severinov K. BREX system of Escherichia coli distinguishes self from non-self by methylation of a specific DNA site. Nucleic Acids Res. 2018. PMID: 30418590, doi: 10.1093/nar/gky1125(

  • 09/2018 Teacher-Researcher, Peter the Great Saint-Petersburg Polytechnic University, Department of Biophysics.
  • 06/2014Master of Technical Physics, Peter the Great Saint-Petersburg Polytechnic University, Department of Physical Electronics.
  • 06/2012Bachelor of Physics, Peter the Great Saint-Petersburg Polytechnic University, Department of Physical Electronics.