annafefilova

Anna Fefilova

Research Intern
Center of Life Sciences

Research advisor: Associate professor Timofei Zatsepin

Program entry year: 2014

Graduated from Peter the Great Saint Petersburg Polytechnic University in 2014

Research project: LncRNAs as possible regulators of NF-κB pathway in the liver

Research interests: Regulatory functions of long non-coding RNAs in cells, RNAi-based therapies

Academic mobility:

  1. University: Koch Institute for Integrative Cancer Research at Massachusetts Institute of Technology (MIT), USA

Laboratory: Daniel Anderson Lab, http://anderson-lab.mit.edu/research

Dates: 25.04.2015-25.04.2016

  1. University: Chemistry Department of Boston University, USA

Laboratory: Arturo Vegas Lab, http://www.avegaslab.com/

Dates: 01.07.2016-31.01.2017 and 01.04.2017-30.11.2017

Publications:

  • M. Smekalova, Y.V. Kotelevtsev, D. Leboeuf, E.Y. Shcherbinina, A.S. Fefilova, T.S. Zatsepin, V. Koteliansky; “LncRNA in the liver: Prospects for fundamental research and therapy by RNA interference”; Biochimie, 131, 159-172, 2016

Conference presentations:

  • Oral presentation “LncRNAs as possible regulators of NF-κb pathway in liver” September 2018 at the conference “Chemistry meets Biomedicine”, Friedrich-Alexander-University of Erlangen-Nürnberg.
  • Fefilova A.S., Smekalova E.M., Bogorad R.L., Whittaker C., Anderson D.G., Koteliansky V.E. “In vivo study of non-canonical functions of eukaryotic translation initiation factor 3 (eIF3) using RNA interference”, 2017, Skoltech and MIT conference “Shaping the future: big data, biomedicine and frontier technology”. Poster presentation.
  • Smekalova E.M., Bogorad R.L., Gerashchenko M.V. , O’Connor P.B., Fefilova A.S., Galdyshev V.N., Baranov P.V., Koteliansky V.E., Anderson D.G “Nanoparticle formulated siRNA based approach to study gene regulatory network associated with the translation initiation factor 3 (eIF3) in liver”, Cold Spring Harbor Laboratory Meetings, Translational Control, 2016. Poster presentation.