Alexander Tyshkovskii

PhD student

Supervisor: Philipp Khaitovich, co-advisor: Vadim Gladyshev, Brigham and Women’s Hospital, Harvard Medical School, Boston, USA.

Entry year to Skoltech – 2014

Graduated with distinction from Lomonosov Moscow State University, Department of Bioengineering and Bioinformatics.

Research project: “Identification of new aging-associated molecular targets based on cross-species analysis of longevity-associated mutations and drugs effect on gene expression level and metabolite profile”

The project is aimed to use confirmed and putative longevity-associated drugs and mutations for identification of new molecular pathways related to aging and new molecular targets for potential intervention. For generalization of our findings different animals at different stages of development will be used during the work. Such project may bring us closer to the understanding of aging mechanisms and even let us discover new drugs for increase of lifespan of human being.

I am doing my PhD project in the laboratory of Vadim Gladyshev in Brigham and Women’s Hospital, Harvard Medical School, Boston. Here is the link to lab web site:

Participation in conferences

Mechanisms of aging, Cold Springs Harbor Laboratory, 2016:

Poster: Gene expression analyses across lifespan-extending interventions identify the associated molecular mechanisms

Russian corporations, universities and science: problems and perspectives of collaboration in innovation sphere (organized by Rostekhnologii State Corporation), 2012:

Report: Identification of a new cell antioxidative defense participant and its contribution to enhancement of biotechnological processes productivity – conference award for the best report

XVIII International conference of students, graduate students and young scientists ‘Lomonosov-2011’:

Report: Correlation between gene expression level changes during oxidative stress response and content of amino acids in coding proteins in Saccharomyces cerevisiae cells – conference award for the best report

IV International molecular genetics school of young scientists Genomics and Cell Biology, 2010:

Report: Telomerase as a marker and target in oncogenesis

XVII International conference of students, graduate students and young scientists ‘Lomonosov-2010’:

Poster: Telomerase as a potential marker for kidney cancer diagnostics

Diploma - My diploma work in Moscow State University was called “Development of mathematical model of TRPV1 channels activation and regulation on peripheral ends of nociceptors and its application for identification of potential analgesia candidates” and was done under supervision of Dr. Oleg Demin in Institute for Systems Biology (ISB).

Nomination for Presidential Award for Young Scientists in Fields of Science and Innovation, 2014
Semifinalist of MIT$100K Entrepreneurship Competition Pitch contest, Cambridge, 2013-2014
Russian Government Fellowship, 2012-2013
Russian Government Fellowship, 2011-2012